As a child, I spent many summer days at the beach in southern California. I remember playing in the surf, collecting shells, watching sea lions, and seeing the white noses of the lifeguards. In those days, lifeguards smeared thick, white zinc oxide paste on their noses to protect themselves from getting sunburned
My nose, smeared in Zinka Sunblock, which contains zinc oxide particles
When my kids were young there was a brief period when colored zinc oxide sunblock seemed to be in vogue
My nose, smeared in colored Zinka Sunblock
Nowadays, we still use zinc oxide in sunblocks, but it’s no longer white or colored; it’s transparent! How can this be? It’s the same material!!
If you took high school chemistry, you might remember using pH indicator strips. You’d take a piece of the specially treated paper, dip it in your solution, and watch it change color depending on whether you had an acid or base.
At the time, you might have been more excited by the fact that the paper changed color than about what you were accomplishing with the task. However, chemical sensors aren’t just visually appealing—they also play an important role in monitoring conditions both inside and outside of the lab. Continue reading
During my time in the Marine Corps I met several people that lost limbs in the war. I made the decision to leave the service to get my degree. Inspired by my fellow soldiers, my ultimate goal is to start a company making prosthetics and bionic limbs, hopefully making their lives a little bit easier.
Flight into Iraq
One problem with prosthetics is that they can only be worn for a short period of time. This is partly due to discomfort issues. However, a more serious concern is infection. Our bodies sweat and move constantly, so there is an increased risk of irritation and subsequent infection with long-term prosthetic use.
Several products have been created and tested that help reduce infections caused by implantable medical devices. Some of these products use silver nanoparticles. As we’ve discussed before on this blog (entry 1, entry 2), silver nanoparticles fight microbes by slowly releasing silver ions that are toxic to bacteria and other microbial pests. The surface of implantable medical devices can be coated with silver nanoparticles, and the slow release of silver ions helps keep the area of implantation free of infection.
Perhaps one day prosthetic materials coated with silver nanoparticles will be widely available (perhaps made by my company!). While I have only been conducting nanoparticle research through the Research Experiences for Veterans program for about two months, I have learned a tremendous amount about some of the exciting advances in nanotechnology. This is just a glimpse into my first exciting idea, and I’m sure to have more as my technical experience grows.
Scientists have discovered that tiny particles of gold injected into fat tissues can offer a new and potentially safer way to carry out liposuction procedures. Liposuction by definition is the process of removing excess fat found underneath the skin by suction. Although liposuction has a reputation as a low risk cosmetic surgery, this procedure is not without its problems. One of the primary problems stems from the fact that fat is not an isolated feature of the body. Simply put, nerves and other closely located tissues may be removed along with the fat. Recent research shows that gold nanoparticles may be the solution to this problem. Problems associated with liposuction deserve some attention, as this is one of the most commonly performed cosmetic surgeries and people ranging from ages twelve to eighty-seven have had this procedure.
While the word “bacteria” conjures images of human illness and death for many people, the vast majority of bacteria in the world allow for the healthy functioning of humans and ecosystems. The way they do this ranges from breaking down food in animals’ digestive systems (yes, even ours) to cycling life-giving chemical elements from things like sediment and rocks back into living food chains. Today I will be discussing only one aspect of only one of our hidden little friends—Shewanella oneidensis’ power to mobilize the critical element iron for use by other organisms. Without Shewanella, you and I and most other life on earth would have a big problem on our hands.
There is an ovarian cancer drug called DOXIL that is delivered to cells in a nanoparticle made of molecules of fat. But, how does the nanoparticle enter the cell?
According to a recent study that uses computers to model this process, there are mainly 3 ways in which scientists think a nanoparticle can enter the cell: penetration, endocytosis, and semi-endocytosis.
In order to enter a cell, the nanoparticle has to cross the cell membrane, which separates the internal components of the cell from the outside.
Endocytosis and Semi-Endocytosis
The most exciting moments of my pre-college education were from a field trip to the geology department of Augustana College where I was shown around the facilities by Dr. Michael Wolf. He showed me tools that scientists use to experiment with rocks under intense heat and pressure.